DegronMD - Q8TB96(ITFG1)

ITFG1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P318L	TCGA-D6-6516	HNSC	TCGA	FVPFVD	LIG_APCC_ABBA_1	316:321	Mutation altering degron motif	0.6471
p.P318L	DO15623	HNSC	ICGC	FVPFVD	LIG_APCC_ABBA_1	316:321	Mutation altering degron motif	0.6471
p.P329Q	DO233160	GACA	ICGC	FVPFVD	LIG_APCC_ABBA_1	316:321	Mutation rewiring degron network	0.1111
p.P318S	DO228138	PBCA	ICGC	FVPFVD	LIG_APCC_ABBA_1	316:321	Mutation altering degron motif	0.6752
p.K310R	SIDM00660	Colorectal Carcinoma	GDSC	FVPFVD	LIG_APCC_ABBA_1	316:321	Mutation substituting flanking lysine	0.2778
p.V320A	SIDM00769	Non-Small Cell Lung Carcinoma	GDSC	FVPFVD	LIG_APCC_ABBA_1	316:321	Mutation altering degron motif	0.5825
p.T312S	SIDM00730	Small Cell Lung Carcinoma	GDSC	FVPFVD	LIG_APCC_ABBA_1	316:321	Mutation rewiring degron network	0.2222
p.T312S	ACH-000610	Lung Cancer	CCLE	FVPFVD	LIG_APCC_ABBA_1	316:321	Mutation rewiring degron network	0.2222
p.T312S	NCI-H2227	lung	COSMIC	FVPFVD	LIG_APCC_ABBA_1	316:321	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc