DegronMD - Q8TBA6(GOLGA5)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V202L	TCGA-A8-A06Y	BRCA	TCGA	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation altering degron motif	0.5654
p.V202L	DO4872	BRCA	ICGC	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation altering degron motif	0.5654
p.P209R	TCGA-CG-5719	STAD	TCGA	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation rewiring degron network	0.1389
p.P209R	DO38827	STAD	ICGC	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation rewiring degron network	0.1389
p.S190I	DO222478	ESCA	ICGC	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation rewiring degron network	0.1111
p.K199E	SIDM00144	Non-Small Cell Lung Carcinoma	GDSC	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation altering degron motif	0.7022
p.K199E	ACH-000463	Lung Cancer	CCLE	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation altering degron motif	0.7022
p.K199E	NCI-H460	lung	COSMIC	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation altering degron motif	0.7022
p.S190R	SIDM00374	B-Cell Non-Hodgkin's Lymphoma	GDSC	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation rewiring degron network	0.1111
p.S190R	SIDM01569	Hepatocellular Carcinoma	GDSC	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation rewiring degron network	0.1111
p.S190R	ACH-000734	Liver Cancer	CCLE	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation rewiring degron network	0.1111
p.S190R	ACH-002062	Lymphoma	CCLE	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation rewiring degron network	0.1111
p.S190R	SLVL	haematopoietic and lymphoid tissue	COSMIC	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation rewiring degron network	0.1111
p.E192D	SIDM01770	Gastric Carcinoma	GDSC	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation rewiring degron network	0.1667
p.E192D	ACH-000908	Gastric Cancer	CCLE	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation rewiring degron network	0.1667
p.G193V	SIDM01752	Pancreatic Carcinoma	GDSC	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation rewiring degron network	0.1944
p.G193V	ACH-000685	Pancreatic Cancer	CCLE	SKENV	DEG_APCC_KENBOX_2	198:202	Mutation rewiring degron network	0.1944

Kaplan plot for GOLGA5 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

GOLGA5

UniProt ID: Q8TBA6

Entrez ID: 9950

Protein name: Golgin subfamily A member 5 (Cell proliferation-inducing gene 31 protein) (Golgin-84) (Protein Ret-II) (RET-fused gene 5 protein)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for GOLGA5 in