DegronMD - Q8TBZ2(MYCBPAP)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L570I	TCGA-19-5956	GBM	TCGA	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.2222
p.L570I	DO13863	GBM	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.2222
p.R584S	TCGA-A5-A0G2	UCEC	TCGA	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.2222
p.S589I	TCGA-AP-A1E0	UCEC	TCGA	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.0833
p.E588K	TCGA-DK-A3X1	BLCA	TCGA	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.1111
p.E588K	DO447	BLCA	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.1111
p.V579I	TCGA-FV-A496	LIHC	TCGA	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation altering degron motif	0.7076
p.V579I	DO44966	LIHC	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation altering degron motif	0.7076
p.S574F	TCGA-HC-7233	PRAD	TCGA	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation altering degron motif	0.7982
p.L588F	DO225332	BRCA	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.1111
p.R579H	DO225346	BRCA	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation altering degron motif	0.7133
p.R579H	DO220867	MELA	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation altering degron motif	0.7133
p.R564C	DO233728	GACA	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.0556
p.E590K	DO233869	GACA	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.0556
p.P577L	DO16023	HNSC	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation altering degron motif	0.7582
p.A586S	DO229022	LICA	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.1667
p.R579C	DO35186	PACA	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation altering degron motif	0.719
p.P583H	DO42600	UCEC	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.25
p.A586V	DO41271	UCEC	ICGC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.1667
p.I565V	SIDM00530	Esophageal Carcinoma	GDSC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.0833
p.I565V	ACH-001544	Esophageal Cancer	CCLE	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.0833
p.I565V	KYAE-1	oesophagus	COSMIC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.0833
p.S589N	SIDM00683	Prostate Carcinoma	GDSC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.0833
p.S589N	LNCaP-Clone-FGC	prostate	COSMIC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.0833
p.L571V	OVCAR-5	ovary	COSMIC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.25
p.L571V	RD	soft tissue	COSMIC	VLTPERT	DEG_SCF_FBW7_1	574:580	Mutation rewiring degron network	0.25

Kaplan plot for MYCBPAP in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MYCBPAP

UniProt ID: Q8TBZ2

Entrez ID: 84073

Protein name: MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for MYCBPAP in