DegronMD - Q8TC76(FAM110B)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V209L	TCGA-21-1070	LUSC	TCGA	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.1389
p.V209L	DO27088	LUSC	ICGC	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.1389
p.P222H	TCGA-39-5016	LUSC	TCGA	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.2778
p.P222H	DO26701	LUSC	ICGC	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.2778
p.S220P	TCGA-A5-A1OF	UCEC	TCGA	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation altering degron motif	0.6752
p.S220P	DO42568	UCEC	ICGC	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation altering degron motif	0.6752
p.P211H	TCGA-AP-A054	UCEC	TCGA	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.1944
p.P211H	DO42256	UCEC	ICGC	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.1944
p.S208R	TCGA-AX-A1C5	UCEC	TCGA	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.1111
p.S208R	DO41422	UCEC	ICGC	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.1111
p.V206A	TCGA-CV-7247	HNSC	TCGA	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.0556
p.V206A	DO14982	HNSC	ICGC	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.0556
p.S220C	TCGA-NJ-A4YG	LUAD	TCGA	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation altering degron motif	0.7541
p.S220C	DO218941	LUAD	ICGC	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation altering degron motif	0.7541
p.L212F	DO230335	COCA	ICGC	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.2222
p.P228S	DO220862	MELA	ICGC	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.1111
p.V209M	SIDM00280	Gastric Carcinoma	GDSC	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.1389
p.V209M	ACH-000560	Gastric Cancer	CCLE	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.1389
p.V209M	ECC10	stomach	COSMIC	PCSSS	DEG_SPOP_SBC_1	216:220	Mutation rewiring degron network	0.1389

Kaplan plot for FAM110B in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

FAM110B

UniProt ID: Q8TC76

Entrez ID: 90362

Protein name: Protein FAM110B

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for FAM110B in