DegronMD - Q8TCZ2(CD99L2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H97N	TCGA-56-8625	LUSC	TCGA	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.3056
p.H97N	DO229038	LICA	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.3056
p.H97N	DO45515	LUSC	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.3056
p.P111A	TCGA-91-6829	LUAD	TCGA	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.0833
p.P111A	DO23564	LUAD	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.0833
p.T101M	TCGA-AD-6895	COAD	TCGA	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation altering degron motif	0.7423
p.T101M	DO8938	COAD	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation altering degron motif	0.7423
p.T107N	TCGA-C4-A0EZ	BLCA	TCGA	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.1944
p.T107N	DO476	BLCA	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.1944
p.K103N	TCGA-CK-5913	COAD	TCGA	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.3056
p.K103N	DO8826	COAD	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.3056
p.T99I	TCGA-EB-A24D	SKCM	TCGA	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation altering degron motif	0.5966
p.T99I	DO37440	SKCM	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation altering degron motif	0.5966
p.S112F	DO217962	BRCA	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.0556
p.G90V	DO225215	BRCA	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.1111
p.G90V	DO227836	BRCA	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.1111
p.Y98H	DO233784	GACA	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation altering degron motif	0.7229
p.S99C	DO233852	GACA	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation altering degron motif	0.7541
p.G99V	DO22237	LGG	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation altering degron motif	0.7532
p.T100N	DO229032	LICA	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation altering degron motif	0.7055
p.G105V	DO23717	LUAD	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.25
p.R97P	DO23586	LUAD	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.3056
p.D103N	DO37412	SKCM	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.3056
p.V109M	DO51761	STAD	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.1389
p.D103G	DO222356	STAD	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.3056
p.K91N	DO39720	THCA	ICGC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.1389
p.T112A	SIDM01247	Burkitt's Lymphoma	GDSC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.0556
p.G94R	SIDM00391	Plasma Cell Myeloma	GDSC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.2222
p.G94R	SK-MM-2	haematopoietic and lymphoid tissue	COSMIC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.2222
p.G90R	ACH-000363	Myeloma	CCLE	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.1111
p.G90R	SK-MM-2	haematopoietic and lymphoid tissue	COSMIC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.1111
p.I104K	ACH-000394	Lung Cancer	CCLE	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.2778
p.I104K	NCI-H2081	lung	COSMIC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.2778
p.I90T	ACH-000831	Endometrial/Uterine Cancer	CCLE	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.1111
p.I90T	ACH-002201	Cervical Cancer	CCLE	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.1111
p.I90T	TC-YIK	cervix	COSMIC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.1111
p.G106W	ACH-000833	Sarcoma	CCLE	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.2222
p.G106W	SJRH30	soft tissue	COSMIC	VTTTT	DEG_SPOP_SBC_1	98:102	Mutation rewiring degron network	0.2222

Kaplan plot for CD99L2 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CD99L2

UniProt ID: Q8TCZ2

Entrez ID: 83692

Protein name: CD99 antigen-like protein 2 (MIC2-like protein 1) (CD antigen CD99)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CD99L2 in