DegronMD - Q8TDN2(KCNV2)

KCNV2

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E544D	TCGA-AA-3510	COAD	TCGA	PQLTPRQE	DEG_SCF_FBW7_2	537:544	Mutation altering degron motif	0.6758
p.E544D	DO7783	COAD	ICGC	PQLTPRQE	DEG_SCF_FBW7_2	537:544	Mutation altering degron motif	0.6758
p.E544D	SIDM00193	Colorectal Carcinoma	GDSC	PQLTPRQE	DEG_SCF_FBW7_2	537:544	Mutation altering degron motif	0.6758
p.E544D	SIDM01588	Endometrial Carcinoma	GDSC	PQLTPRQE	DEG_SCF_FBW7_2	537:544	Mutation altering degron motif	0.6758
p.E544D	ACH-000991	Colon/Colorectal Cancer	CCLE	PQLTPRQE	DEG_SCF_FBW7_2	537:544	Mutation altering degron motif	0.6758
p.E544D	ACH-000993	Endometrial/Uterine Cancer	CCLE	PQLTPRQE	DEG_SCF_FBW7_2	537:544	Mutation altering degron motif	0.6758
p.E544D	SNU-81	large intestine	COSMIC	PQLTPRQE	DEG_SCF_FBW7_2	537:544	Mutation altering degron motif	0.6758
p.Q538H	DO229045	LICA	ICGC	PQLTPRQE	DEG_SCF_FBW7_2	537:544	Mutation altering degron motif	0.647
p.Q538H	DO232761	PBCA	ICGC	PQLTPRQE	DEG_SCF_FBW7_2	537:544	Mutation altering degron motif	0.647
p.N536S	SIDM00183	Small Cell Lung Carcinoma	GDSC	PQLTPRQE	DEG_SCF_FBW7_2	537:544	Mutation rewiring degron network	0.3056
p.N536S	SIDM01648	Non-Cancerous	GDSC	PQLTPRQE	DEG_SCF_FBW7_2	537:544	Mutation rewiring degron network	0.3056

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc