DegronMD - Q8TDR0(TRAF3IP1)

TRAF3IP1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E298K	TCGA-19-5956	GBM	TCGA	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation rewiring degron network	0.1111
p.E298K	DO13863	GBM	ICGC	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation rewiring degron network	0.1111
p.E303K	TCGA-34-5928	LUSC	TCGA	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation rewiring degron network	0.25
p.E303K	DO27461	LUSC	ICGC	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation rewiring degron network	0.25
p.G310R	TCGA-AP-A1DK	UCEC	TCGA	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation altering degron motif	0.7568
p.G310R	DO42033	UCEC	ICGC	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation altering degron motif	0.7568
p.G319E	TCGA-AX-A2HC	UCEC	TCGA	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation rewiring degron network	0.1111
p.G319E	DO41572	UCEC	ICGC	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation rewiring degron network	0.1111
p.M312I	DO229024	LICA	ICGC	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation rewiring degron network	0.3056
p.M312I	DO229208	THCA	ICGC	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation rewiring degron network	0.3056
p.N296T	SIDM00770	Small Cell Lung Carcinoma	GDSC	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation rewiring degron network	0.0556
p.R297G	SIDM00927	Small Cell Lung Carcinoma	GDSC	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation rewiring degron network	0.0833
p.R297G	ACH-000871	Lung Cancer	CCLE	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation rewiring degron network	0.0833
p.R297G	NCI-H510A	lung	COSMIC	SASSGE	DEG_Kelch_Keap1_1	306:311	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc