DegronMD - Q8TEM1(NUP210)

NUP210

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T1833M	TCGA-2J-AAB6	PAAD	TCGA	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation rewiring degron network	0.0556
p.T1833M	DO51656	PAAD	ICGC	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation rewiring degron network	0.0556
p.A1857T	TCGA-AX-A1CE	UCEC	TCGA	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation rewiring degron network	0.0833
p.A1857T	DO42280	UCEC	ICGC	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation rewiring degron network	0.0833
p.R1835L	TCGA-D3-A2JK	SKCM	TCGA	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation rewiring degron network	0.1111
p.R1835L	DO37619	SKCM	ICGC	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation rewiring degron network	0.1111
p.L1837R	DO233840	GACA	ICGC	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation rewiring degron network	0.1667
p.L1837R	SIDM01312	Esophageal Carcinoma	GDSC	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation rewiring degron network	0.1667
p.R1835Q	DO229036	LICA	ICGC	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation rewiring degron network	0.1111
p.R1835Q	SIDM00522	Small Cell Lung Carcinoma	GDSC	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation rewiring degron network	0.1111
p.R1835Q	DMS-273	lung	COSMIC	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation rewiring degron network	0.1111
p.P1845T	DO229045	LICA	ICGC	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation altering degron motif	0.7031
p.T1844M	SIDM01735	Biliary Tract Carcinoma	GDSC	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation altering degron motif	0.8534
p.R1835W	ACH-001656	Leukemia	CCLE	LTPRAS	DEG_SCF_FBW7_1	1843:1848	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc