DegronMD - Q8TF44(C2CD4C)

C2CD4C

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R359H	DO222973	BTCA	ICGC	RRPVFNE	LIG_APCC_ABBAyCdc20_2	367:373	Mutation rewiring degron network	0.1111
p.R359H	ACH-001518	Endometrial/Uterine Cancer	CCLE	RRPVFNE	LIG_APCC_ABBAyCdc20_2	367:373	Mutation rewiring degron network	0.1111
p.G379S	DO233652	GACA	ICGC	RRPVFNE	LIG_APCC_ABBAyCdc20_2	367:373	Mutation rewiring degron network	0.1667
p.R368C	DO233764	GACA	ICGC	RRPVFNE	LIG_APCC_ABBAyCdc20_2	367:373	Mutation altering degron motif	0.719
p.F371L	DO229041	LICA	ICGC	RRPVFNE	LIG_APCC_ABBAyCdc20_2	367:373	Mutation altering degron motif	0.6981
p.N372K	DO229041	LICA	ICGC	RRPVFNE	LIG_APCC_ABBAyCdc20_2	367:373	Mutation altering degron motif	0.5806
p.R367H	ACH-000956	Prostate Cancer	CCLE	RRPVFNE	LIG_APCC_ABBAyCdc20_2	367:373	Mutation altering degron motif	0.8244
p.A383S	ACH-001529	Endometrial/Uterine Cancer	CCLE	RRPVFNE	LIG_APCC_ABBAyCdc20_2	367:373	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc