DegronMD - Q8WU08(STK32A)

STK32A

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V18A	TCGA-AA-3663	COAD	TCGA	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.2222
p.V18A	DO9346	COAD	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.2222
p.H22Y	TCGA-AP-A1DK	UCEC	TCGA	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.1111
p.H22Y	DO42033	UCEC	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.1111
p.P9R	TCGA-CG-5733	STAD	TCGA	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation altering degron motif	0.6401
p.P9R	DO38551	STAD	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation altering degron motif	0.6401
p.A3V	TCGA-E2-A574	BRCA	TCGA	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation substituting flanking lysine	0.3056
p.A3V	DO49022	BRCA	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation substituting flanking lysine	0.3056
p.P10Q	TCGA-GN-A26C	SKCM	TCGA	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation altering degron motif	0.5924
p.P10Q	DO37782	SKCM	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation altering degron motif	0.5924
p.F12V	DO234413	ESAD	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation altering degron motif	0.7068
p.R7K	SIDM01617	Endometrial Carcinoma	GDSC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.3056
p.R7K	ACH-000994	Endometrial/Uterine Cancer	CCLE	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc