DegronMD - Q8WU90(ZC3H15)

ZC3H15

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R134Q	TCGA-A5-A2K3	UCEC	TCGA	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation altering degron motif	0.6218
p.R134Q	DO230315	COCA	ICGC	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation altering degron motif	0.6218
p.R134Q	DO43899	UCEC	ICGC	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation altering degron motif	0.6218
p.A140V	TCGA-AP-A1E1	UCEC	TCGA	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation rewiring degron network	0.3056
p.A140V	DO43226	UCEC	ICGC	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation rewiring degron network	0.3056
p.R141I	TCGA-EO-A22T	UCEC	TCGA	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation rewiring degron network	0.2778
p.R141I	DO42320	UCEC	ICGC	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation rewiring degron network	0.2778
p.D142H	TCGA-OL-A5RW	BRCA	TCGA	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation rewiring degron network	0.25
p.D142H	DO44238	BRCA	ICGC	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation rewiring degron network	0.25
p.D139Y	DO225167	BRCA	ICGC	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation altering degron motif	0.7325
p.M128I	DO228976	LICA	ICGC	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation rewiring degron network	0.1944
p.C131F	DO229019	LICA	ICGC	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation rewiring degron network	0.2778
p.D148H	DO50974	LICA	ICGC	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation rewiring degron network	0.0833
p.Y137S	DO221118	MALY	ICGC	KRSVYID	LIG_APCC_ABBAyCdc20_2	133:139	Mutation altering degron motif	0.8231

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*NOTE: the Kaplan plots were collected from OncoLnc