DegronMD - Q8WUJ1(CYB5D2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L264I	TCGA-19-5956	GBM	TCGA	NLAEYTGCP	CBL_PTK	246:254	Mutation rewiring degron network	0.0556
p.L264I	DO13863	GBM	ICGC	NLAEYTGCP	CBL_PTK	246:254	Mutation rewiring degron network	0.0556
p.H236N	TCGA-24-1474	OV	TCGA	NLAEYTGCP	CBL_PTK	246:254	Mutation rewiring degron network	0.0556
p.H236N	DO31919	OV	ICGC	NLAEYTGCP	CBL_PTK	246:254	Mutation rewiring degron network	0.0556
p.P254Q	TCGA-EE-A2M8	SKCM	TCGA	NLAEYTGCP	CBL_PTK	246:254	Mutation altering degron motif	0.7035
p.P254Q	DO38075	SKCM	ICGC	NLAEYTGCP	CBL_PTK	246:254	Mutation altering degron motif	0.7035
p.F262L	DO23222	LINC	ICGC	NLAEYTGCP	CBL_PTK	246:254	Mutation rewiring degron network	0.1111
p.C253W	ACH-000971	Colon/Colorectal Cancer	CCLE	NLAEYTGCP	CBL_PTK	246:254	Mutation altering degron motif	0.5889

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons