DegronMD - Q8WUU5(GATAD1)

GATAD1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V265F	DO228948	LICA	ICGC	VGPTPAIT	DEG_SCF_FBW7_1	253:260	Mutation rewiring degron network	0.1944
p.G254W	DO229018	LICA	ICGC	VGPTPAIT	DEG_SCF_FBW7_1	253:260	Mutation altering degron motif	0.6714
p.V253F	DO229019	LICA	ICGC	VGPTPAIT	DEG_SCF_FBW7_1	253:260	Mutation altering degron motif	0.7068
p.A258S	DO229008	LICA	ICGC	VGPTPAIT	DEG_SCF_FBW7_1	253:260	Mutation altering degron motif	0.6477
p.A266V	DO220889	MELA	ICGC	VGPTPAIT	DEG_SCF_FBW7_1	253:260	Mutation rewiring degron network	0.1667
p.P257L	SIDM01121	Small Cell Lung Carcinoma	GDSC	VGPTPAIT	DEG_SCF_FBW7_1	253:260	Mutation altering degron motif	0.7582
p.P257L	ACH-000358	Lung Cancer	CCLE	VGPTPAIT	DEG_SCF_FBW7_1	253:260	Mutation altering degron motif	0.7582
p.P257L	NCI-H69	lung	COSMIC	VGPTPAIT	DEG_SCF_FBW7_1	253:260	Mutation altering degron motif	0.7582
p.E245Q	SIDM00749	Non-Small Cell Lung Carcinoma	GDSC	VGPTPAIT	DEG_SCF_FBW7_1	253:260	Mutation rewiring degron network	0.1111
p.E245Q	ACH-000916	Lung Cancer	CCLE	VGPTPAIT	DEG_SCF_FBW7_1	253:260	Mutation rewiring degron network	0.1111
p.E245Q	NCI-H1573	lung	COSMIC	VGPTPAIT	DEG_SCF_FBW7_1	253:260	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc