DegronMD - Q8WV99(ZFAND2B)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A148V	TCGA-06-5416	GBM	TCGA	STSTVPSP	DEG_COP1_1	157:164	Mutation rewiring degron network	0.0833
p.A148V	DO10880	GBM	ICGC	STSTVPSP	DEG_COP1_1	157:164	Mutation rewiring degron network	0.0833
p.A148V	DO50669	ORCA	ICGC	STSTVPSP	DEG_COP1_1	157:164	Mutation rewiring degron network	0.0833
p.T158A	TCGA-12-5295	GBM	TCGA	STSTVPSP	DEG_COP1_1	157:164	Mutation altering degron motif	0.7139
p.T158A	DO11848	GBM	ICGC	STSTVPSP	DEG_COP1_1	157:164	Mutation altering degron motif	0.7139
p.I149T	TCGA-A3-3317	KIRC	TCGA	STSTVPSP	DEG_COP1_1	157:164	Mutation rewiring degron network	0.1111
p.I149T	TCGA-B0-4852	KIRC	TCGA	STSTVPSP	DEG_COP1_1	157:164	Mutation rewiring degron network	0.1111
p.I149T	DO19703	KIRC	ICGC	STSTVPSP	DEG_COP1_1	157:164	Mutation rewiring degron network	0.1111
p.I149S	TCGA-BQ-5881	KIRP	TCGA	STSTVPSP	DEG_COP1_1	157:164	Mutation rewiring degron network	0.1111
p.I149S	DO20865	KIRP	ICGC	STSTVPSP	DEG_COP1_1	157:164	Mutation rewiring degron network	0.1111
p.S159G	TCGA-CJ-5677	KIRC	TCGA	STSTVPSP	DEG_COP1_1	157:164	Mutation altering degron motif	0.5882
p.S159G	DO19278	KIRC	ICGC	STSTVPSP	DEG_COP1_1	157:164	Mutation altering degron motif	0.5882
p.C171Y	TCGA-EY-A215	UCEC	TCGA	STSTVPSP	DEG_COP1_1	157:164	Mutation rewiring degron network	0.1389
p.C171Y	DO42665	UCEC	ICGC	STSTVPSP	DEG_COP1_1	157:164	Mutation rewiring degron network	0.1389
p.V161I	TCGA-N7-A4Y0	UCS	TCGA	STSTVPSP	DEG_COP1_1	157:164	Mutation altering degron motif	0.7076
p.A147T	DO222794	COCA	ICGC	STSTVPSP	DEG_COP1_1	157:164	Mutation rewiring degron network	0.0556
p.S159I	DO229015	LICA	ICGC	STSTVPSP	DEG_COP1_1	157:164	Mutation altering degron motif	0.623
p.M168I	DO229025	LICA	ICGC	STSTVPSP	DEG_COP1_1	157:164	Mutation rewiring degron network	0.2222

Kaplan plot for ZFAND2B in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ZFAND2B

UniProt ID: Q8WV99

Entrez ID: 130617

Protein name: AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ZFAND2B in