DegronMD - Q8WVJ2(NUDCD2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E125Q	TCGA-78-7149	LUAD	TCGA	QKENP	DEG_APCC_KENBOX_2	128:132	Mutation rewiring degron network	0.25
p.R120K	TCGA-DF-A2KU	UCEC	TCGA	QKENP	DEG_APCC_KENBOX_2	128:132	Mutation rewiring degron network	0.1111
p.F127I	TCGA-DX-A8BP	SARC	TCGA	QKENP	DEG_APCC_KENBOX_2	128:132	Mutation rewiring degron network	0.3056
p.N119Y	DO1579	BRCA	ICGC	QKENP	DEG_APCC_KENBOX_2	128:132	Mutation rewiring degron network	0.0833
p.G124E	DO50329	ESAD	ICGC	QKENP	DEG_APCC_KENBOX_2	128:132	Mutation rewiring degron network	0.2222
p.E131Q	DO47723	STAD	ICGC	QKENP	DEG_APCC_KENBOX_2	128:132	Mutation altering degron motif	0.6744
p.D126N	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	QKENP	DEG_APCC_KENBOX_2	128:132	Mutation rewiring degron network	0.2778
p.S128L	CP66-MEL	skin	COSMIC	QKENP	DEG_APCC_KENBOX_2	128:132	Mutation altering degron motif	0.7667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons