DegronMD - Q8WWX9(SELENOM)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D121N	SIDM02050	Colorectal Carcinoma	GDSC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation altering degron motif	0.5821
p.V129M	SIDM02059	Colorectal Carcinoma	GDSC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation rewiring degron network	0.2778
p.V129M	SIDM00503	Gastric Carcinoma	GDSC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation rewiring degron network	0.2778
p.V129M	FU97	stomach	COSMIC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation rewiring degron network	0.2778
p.V124A	SIDM01307	Colorectal Carcinoma	GDSC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation altering degron motif	0.6936
p.V124A	SIDM01086	B-Lymphoblastic Leukemia	GDSC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation altering degron motif	0.6936
p.V124A	RS4-11	haematopoietic and lymphoid tissue	COSMIC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation altering degron motif	0.6936
p.P135S	SIDM00054	Pancreatic Carcinoma	GDSC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation rewiring degron network	0.1111
p.P135S	SIDM01180	Hepatocellular Carcinoma	GDSC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation rewiring degron network	0.1111
p.P135S	SIDM00018	Acute Myeloid Leukemia	GDSC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation rewiring degron network	0.1111
p.P135S	SIDM00604	Oral Cavity Carcinoma	GDSC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation rewiring degron network	0.1111
p.P135S	SIDM01473	Plasma Cell Myeloma	GDSC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation rewiring degron network	0.1111
p.V123A	RS4-11	haematopoietic and lymphoid tissue	COSMIC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation altering degron motif	0.6936
p.V128M	FU97	stomach	COSMIC	APDAQVPPE	DEG_SIAH_1	119:127	Mutation rewiring degron network	0.3056

Kaplan plot for SELENOM in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SELENOM

UniProt ID: Q8WWX9

Entrez ID: 140606

Protein name: Selenoprotein M (SelM)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SELENOM in