DegronMD - Q8WYP3(RIN2)

RIN2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S65R	TCGA-AP-A1DV	UCEC	TCGA	DSGYDS	DEG_SCF_TRCP1_1	74:79	Mutation rewiring degron network	0.0833
p.V89A	TCGA-G4-6588	COAD	TCGA	DSGYDS	DEG_SCF_TRCP1_1	74:79	Mutation rewiring degron network	0.0556
p.T87R	TCGA-UE-A6QU	SARC	TCGA	DSGYDS	DEG_SCF_TRCP1_1	74:79	Mutation rewiring degron network	0.1111
p.E66Q	DO2020	BRCA	ICGC	DSGYDS	DEG_SCF_TRCP1_1	74:79	Mutation rewiring degron network	0.1111
p.Y77C	DO15286	HNSC	ICGC	DSGYDS	DEG_SCF_TRCP1_1	74:79	Mutation altering degron motif	0.7087
p.R89L	DO228971	LICA	ICGC	DSGYDS	DEG_SCF_TRCP1_1	74:79	Mutation rewiring degron network	0.0556
p.R89L	DO229032	LICA	ICGC	DSGYDS	DEG_SCF_TRCP1_1	74:79	Mutation rewiring degron network	0.0556
p.A72S	DO229038	LICA	ICGC	DSGYDS	DEG_SCF_TRCP1_1	74:79	Mutation rewiring degron network	0.2778
p.S81Y	DO37431	SKCM	ICGC	DSGYDS	DEG_SCF_TRCP1_1	74:79	Mutation rewiring degron network	0.2778
p.D88V	DO41355	UCEC	ICGC	DSGYDS	DEG_SCF_TRCP1_1	74:79	Mutation rewiring degron network	0.0833
p.R73W	LS-180	large intestine	COSMIC	DSGYDS	DEG_SCF_TRCP1_1	74:79	Mutation rewiring degron network	0.3056
p.D78Y	NCI-H1648	lung	COSMIC	DSGYDS	DEG_SCF_TRCP1_1	74:79	Mutation altering degron motif	0.6214

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*NOTE: the Kaplan plots were collected from OncoLnc