DegronMD - Q92529(SHC3)

SHC3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M453V	TCGA-BS-A0U8	UCEC	TCGA	PRKDLFDMK	DEG_APCC_DBOX_1	446:454	Mutation altering degron motif	0.6097
p.M453V	DO41380	UCEC	ICGC	PRKDLFDMK	DEG_APCC_DBOX_1	446:454	Mutation altering degron motif	0.6097
p.E443D	TCGA-CN-4727	HNSC	TCGA	PRKDLFDMK	DEG_APCC_DBOX_1	446:454	Mutation rewiring degron network	0.25
p.E443D	DO14258	HNSC	ICGC	PRKDLFDMK	DEG_APCC_DBOX_1	446:454	Mutation rewiring degron network	0.25
p.A438V	DO227872	COCA	ICGC	PRKDLFDMK	DEG_APCC_DBOX_1	446:454	Mutation rewiring degron network	0.1111
p.A438V	DO52491	COCA	ICGC	PRKDLFDMK	DEG_APCC_DBOX_1	446:454	Mutation rewiring degron network	0.1111
p.A438V	DO228261	LICA	ICGC	PRKDLFDMK	DEG_APCC_DBOX_1	446:454	Mutation rewiring degron network	0.1111
p.S445R	DO228952	LICA	ICGC	PRKDLFDMK	DEG_APCC_DBOX_1	446:454	Mutation rewiring degron network	0.3056
p.S444R	DO229027	LICA	ICGC	PRKDLFDMK	DEG_APCC_DBOX_1	446:454	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc