DegronMD - Q92698(RAD54L)

RAD54L

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q42R	TCGA-12-0657	GBM	TCGA	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation rewiring degron network	0.0833
p.Q42R	DO13911	GBM	ICGC	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation rewiring degron network	0.0833
p.Q69H	TCGA-B5-A11U	UCEC	TCGA	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation rewiring degron network	0.0556
p.Q69H	DO227646	COCA	ICGC	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation rewiring degron network	0.0556
p.Q69H	DO40804	UCEC	ICGC	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation rewiring degron network	0.0556
p.L55F	TCGA-DK-A3WW	BLCA	TCGA	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation altering degron motif	0.6981
p.L55F	TCGA-LP-A4AV	CESC	TCGA	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation altering degron motif	0.6981
p.L55F	DO481	BLCA	ICGC	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation altering degron motif	0.6981
p.L55F	DO44275	CESC	ICGC	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation altering degron motif	0.6981
p.C46F	DO228978	LICA	ICGC	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation rewiring degron network	0.1944
p.P50S	DO222810	MELA	ICGC	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation rewiring degron network	0.3056
p.P63S	DO224656	PACA	ICGC	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation rewiring degron network	0.2222
p.R52W	SIDM00095	Glioblastoma	GDSC	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation altering degron motif	0.8634
p.R52W	ACH-000504	Brain Cancer	CCLE	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation altering degron motif	0.8634
p.R52W	SNB75	central nervous system	COSMIC	FRKPLSQLT	DEG_APCC_DBOX_1	51:59	Mutation altering degron motif	0.8634

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*NOTE: the Kaplan plots were collected from OncoLnc