DegronMD - Q92729(PTPRU)

PTPRU

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P468L	TCGA-AJ-A3IA	UCEC	TCGA	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation rewiring degron network	0.0556
p.P468L	DO43082	UCEC	ICGC	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation rewiring degron network	0.0556
p.V477I	TCGA-DU-6407	LGG	TCGA	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation rewiring degron network	0.3056
p.V477I	DO22295	LGG	ICGC	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation rewiring degron network	0.3056
p.T481M	TCGA-DX-A3UF	SARC	TCGA	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation altering degron motif	0.7423
p.T481M	DO219982	SARC	ICGC	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation altering degron motif	0.7423
p.E473D	TCGA-J2-A4AD	LUAD	TCGA	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation rewiring degron network	0.1944
p.E473D	DO23915	LUAD	ICGC	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation rewiring degron network	0.1944
p.E469D	DO225448	GACA	ICGC	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation rewiring degron network	0.0833
p.S487I	DO229034	LICA	ICGC	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation altering degron motif	0.7341
p.G488E	DO222753	MELA	ICGC	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation altering degron motif	0.7199
p.K475T	DO232761	PBCA	ICGC	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation substituting flanking lysine	0.3611
p.S493P	ACH-001991	Primary	CCLE	TFQTDEDVPSGI	DEG_COP1_1	478:489	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc