DegronMD - Q92772(CDKL2)

CDKL2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H385Y	TCGA-D5-6540	COAD	TCGA	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.2222
p.H385Y	DO9708	COAD	ICGC	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.2222
p.V402M	TCGA-DT-5265	READ	TCGA	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.0833
p.V402M	TCGA-G9-7509	PRAD	TCGA	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.0833
p.V402M	DO51338	PRAD	ICGC	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.0833
p.V402M	DO36499	READ	ICGC	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.0833
p.V402M	SIDM00347	Esophageal Squamous Cell Carcinoma	GDSC	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.0833
p.V402M	SIDM00249	Esophageal Squamous Cell Carcinoma	GDSC	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.0833
p.V402M	SIDM01608	Endometrial Carcinoma	GDSC	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.0833
p.V402M	ACH-000353	Esophageal Cancer	CCLE	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.0833
p.V402M	ACH-000990	Endometrial/Uterine Cancer	CCLE	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.0833
p.K387T	DO222637	BTCA	ICGC	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.2778
p.C397Y	SIDM01617	Endometrial Carcinoma	GDSC	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.2222
p.C397Y	ACH-000994	Endometrial/Uterine Cancer	CCLE	VPSTS	DEG_SPOP_SBC_1	389:393	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc