DegronMD - Q92777(SYN2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S494F	SIDM00424	B-Cell Non-Hodgkin's Lymphoma	GDSC	PPSSS	DEG_SPOP_SBC_1	484:488	Mutation rewiring degron network	0.1667
p.P478S	SIDM01175	Other Sarcomas	GDSC	PPSSS	DEG_SPOP_SBC_1	484:488	Mutation rewiring degron network	0.1667
p.P478S	SIDM00837	Colorectal Carcinoma	GDSC	PPSSS	DEG_SPOP_SBC_1	484:488	Mutation rewiring degron network	0.1667
p.P478S	SW48	large intestine	COSMIC	PPSSS	DEG_SPOP_SBC_1	484:488	Mutation rewiring degron network	0.1667
p.P478S	SW684	soft tissue	COSMIC	PPSSS	DEG_SPOP_SBC_1	484:488	Mutation rewiring degron network	0.1667
p.Q433H	SIDM00826	Colorectal Carcinoma	GDSC	LSRTPALS	DEG_SCF_FBW7_1	418:425	Mutation rewiring degron network	0.1111
p.P422T	SIDM00138	Non-Small Cell Lung Carcinoma	GDSC	LSRTPALS	DEG_SCF_FBW7_1	418:425	Mutation altering degron motif	0.7031
p.P422T	NCI-H23	lung	COSMIC	LSRTPALS	DEG_SCF_FBW7_1	418:425	Mutation altering degron motif	0.7031

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons