DegronMD - Q92945(KHSRP)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Y149C	TCGA-DU-6392	LGG	TCGA	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.7087
p.Y149C	DO22237	LGG	ICGC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.7087
p.R150S	TCGA-EE-A29E	SKCM	TCGA	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.6316
p.R150S	DO37831	SKCM	ICGC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.6316
p.T146K	DO228948	LICA	ICGC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.6195
p.T146K	DO229028	LICA	ICGC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.6195
p.T143N	DO229045	LICA	ICGC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.7055
p.P152Q	DO44708	LICA	ICGC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.7035
p.L134R	DO23188	LINC	ICGC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation rewiring degron network	0.0833
p.E148D	DO227554	PACA	ICGC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.5647
p.P140T	SIDM00084	Glioblastoma	GDSC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation rewiring degron network	0.25
p.D153G	SIDM00282	Colorectal Carcinoma	GDSC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.7198
p.D153G	ACH-000998	Colon/Colorectal Cancer	CCLE	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.7198
p.D153G	CW-2	large intestine	COSMIC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.7198
p.S144L	SIDM01016	T-Lymphoblastic Leukemia	GDSC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.8778
p.S144L	ACH-000995	Leukemia	CCLE	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.8778
p.S144L	Jurkat	haematopoietic and lymphoid tissue	COSMIC	TSMTEEYRVPDGM	DEG_COP1_1	143:155	Mutation altering degron motif	0.8778

Kaplan plot for KHSRP in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

KHSRP

UniProt ID: Q92945

Entrez ID: 8570

Protein name: Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for KHSRP in