DegronMD - Q93062(RBPMS)

RBPMS

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.F127L	TCGA-AA-3510	COAD	TCGA	LVGTPNPS	DEG_SCF_FBW7_1	110:117	Mutation rewiring degron network	0.0556
p.T103M	TCGA-VQ-A8P2	STAD	TCGA	LVGTPNPS	DEG_SCF_FBW7_1	110:117	Mutation rewiring degron network	0.1389
p.T103M	DO51761	STAD	ICGC	LVGTPNPS	DEG_SCF_FBW7_1	110:117	Mutation rewiring degron network	0.1389
p.A107G	DO233517	PRAD	ICGC	LVGTPNPS	DEG_SCF_FBW7_1	110:117	Mutation substituting flanking lysine	0.3611
p.K107N	SIDM01611	Endometrial Carcinoma	GDSC	LVGTPNPS	DEG_SCF_FBW7_1	110:117	Mutation substituting flanking lysine	0.3611
p.K107N	ACH-000996	Endometrial/Uterine Cancer	CCLE	LVGTPNPS	DEG_SCF_FBW7_1	110:117	Mutation substituting flanking lysine	0.3611
p.V124A	ACH-001991	Primary	CCLE	LVGTPNPS	DEG_SCF_FBW7_1	110:117	Mutation rewiring degron network	0.1389
p.S120R	MCC13	skin	COSMIC	LVGTPNPS	DEG_SCF_FBW7_1	110:117	Mutation rewiring degron network	0.25
p.P114L	LN-18	central nervous system	COSMIC	LVGTPNPS	DEG_SCF_FBW7_1	110:117	Mutation altering degron motif	0.7582
p.M114L	LP-1	haematopoietic and lymphoid tissue	COSMIC	LVGTPNPS	DEG_SCF_FBW7_1	110:117	Mutation altering degron motif	0.711
p.T109P	EJM	haematopoietic and lymphoid tissue	COSMIC	LVGTPNPS	DEG_SCF_FBW7_1	110:117	Mutation blocking ubiquitination signal	0.75

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*NOTE: the Kaplan plots were collected from OncoLnc