DegronMD - Q93097(WNT2B)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R38C	TCGA-BR-4362	STAD	TCGA	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation altering degron motif	0.8301
p.R38C	TCGA-BR-8487	STAD	TCGA	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation altering degron motif	0.8301
p.R38C	DO47867	STAD	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation altering degron motif	0.8301
p.R38C	DO38336	STAD	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation altering degron motif	0.8301
p.R55L	TCGA-CK-4951	COAD	TCGA	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.0556
p.R55L	DO10582	COAD	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.0556
p.S36L	DO48386	BLCA	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.3056
p.S36L	SIDM01619	Endometrial Carcinoma	GDSC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.3056
p.S36L	ACH-000984	Endometrial/Uterine Cancer	CCLE	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.3056
p.R45Q	DO219029	BLCA	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation altering degron motif	0.7329
p.V35I	DO3406	BRCA	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.2778
p.H33D	DO52717	CLLE	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.2222
p.L40V	DO222884	COCA	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation altering degron motif	0.6765
p.G29V	DO229009	LICA	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.1111
p.D31E	DO49127	PACA	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.1667
p.G37A	DO36407	READ	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation altering degron motif	0.754
p.F36V	DO41020	UCEC	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.3056
p.V35A	DO42568	UCEC	ICGC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.2778
p.A28T	SIDM00767	Small Cell Lung Carcinoma	GDSC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.0833
p.A28T	SIDM00176	Chondrosarcoma	GDSC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.0833
p.A28T	SIDM01001	Breast Carcinoma	GDSC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.0833
p.A28T	SIDM00039	Ovarian Carcinoma	GDSC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.0833
p.A28T	SIDM01522	B-Lymphoblastic Leukemia	GDSC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation rewiring degron network	0.0833
p.M40I	HCT-116	large intestine	COSMIC	ARLGLACLL	DEG_APCC_DBOX_1	37:45	Mutation altering degron motif	0.7618

Kaplan plot for WNT2B in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

WNT2B

UniProt ID: Q93097

Entrez ID: 7482

Protein name: Protein Wnt-2b (Protein Wnt-13)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for WNT2B in