DegronMD - Q969S9(GFM2)

GFM2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E257D	TCGA-CN-A63Y	HNSC	TCGA	ERKPLLEMN	DEG_APCC_DBOX_1	257:265	Mutation altering degron motif	0.5647
p.E257D	DO44422	HNSC	ICGC	ERKPLLEMN	DEG_APCC_DBOX_1	257:265	Mutation altering degron motif	0.5647
p.M264I	DO1094	BRCA	ICGC	ERKPLLEMN	DEG_APCC_DBOX_1	257:265	Mutation altering degron motif	0.6507
p.K259N	DO229248	THCA	ICGC	ERKPLLEMN	DEG_APCC_DBOX_1	257:265	Mutation altering degron motif	0.5806
p.P267L	SIDM00181	Bladder Carcinoma	GDSC	ERKPLLEMN	DEG_APCC_DBOX_1	257:265	Mutation rewiring degron network	0.2778
p.P267L	ACH-002266	Bladder Cancer	CCLE	ERKPLLEMN	DEG_APCC_DBOX_1	257:265	Mutation rewiring degron network	0.2778
p.P267L	LB831-BLC	urinary tract	COSMIC	ERKPLLEMN	DEG_APCC_DBOX_1	257:265	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc