DegronMD - Q969Z4(RELT)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E236D	TCGA-AA-A00N	COAD	TCGA	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation altering degron motif	0.6758
p.E236D	TCGA-B5-A1MR	UCEC	TCGA	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation altering degron motif	0.6758
p.E236D	TCGA-CA-6717	COAD	TCGA	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation altering degron motif	0.6758
p.E236D	DO9876	COAD	ICGC	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation altering degron motif	0.6758
p.E236D	DO8264	COAD	ICGC	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation altering degron motif	0.6758
p.E236D	DO41758	UCEC	ICGC	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation altering degron motif	0.6758
p.E242G	TCGA-B0-5707	KIRC	TCGA	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation rewiring degron network	0.2222
p.E242G	DO20733	KIRC	ICGC	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation rewiring degron network	0.2222
p.R229H	TCGA-FI-A2D0	UCEC	TCGA	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation rewiring degron network	0.1944
p.R229H	DO43891	UCEC	ICGC	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation rewiring degron network	0.1944
p.R229L	DO229015	LICA	ICGC	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation rewiring degron network	0.1944
p.L227P	DO229211	THCA	ICGC	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation rewiring degron network	0.1389
p.I224T	SIDM00190	Melanoma	GDSC	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation rewiring degron network	0.0556
p.I224T	SIDM01715	Non-Cancerous	GDSC	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation rewiring degron network	0.0556
p.I224T	SIDM00132	Pancreatic Carcinoma	GDSC	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation rewiring degron network	0.0556
p.I224T	SIDM01502	Endometrial Carcinoma	GDSC	KKENA	DEG_APCC_KENBOX_2	234:238	Mutation rewiring degron network	0.0556

Kaplan plot for RELT in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RELT

UniProt ID: Q969Z4

Entrez ID: 84957

Protein name: Tumor necrosis factor receptor superfamily member 19L (Receptor expressed in lymphoid tissues)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for RELT in