DegronMD - Q96A11(GAL3ST3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A11D	TCGA-66-2755	LUSC	TCGA	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation rewiring degron network	0.1667
p.A11D	DO27365	LUSC	ICGC	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation rewiring degron network	0.1667
p.L33I	TCGA-AN-A046	BRCA	TCGA	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation rewiring degron network	0.1111
p.L33I	TCGA-F5-6814	READ	TCGA	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation rewiring degron network	0.1111
p.L33I	DO1285	BRCA	ICGC	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation rewiring degron network	0.1111
p.L33I	DO36556	READ	ICGC	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation rewiring degron network	0.1111
p.H35Q	DO229018	LICA	ICGC	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation rewiring degron network	0.0556
p.S28R	DO229257	THCA	ICGC	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation rewiring degron network	0.25
p.I34T	DO229242	THCA	ICGC	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation rewiring degron network	0.0833
p.V30A	SIDM00926	Non-Small Cell Lung Carcinoma	GDSC	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation rewiring degron network	0.1944
p.V30A	ACH-000924	Lung Cancer	CCLE	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation rewiring degron network	0.1944
p.V30A	NCI-H2172	lung	COSMIC	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation rewiring degron network	0.1944
p.L23P	SIDM01003	T-Lymphoblastic Leukemia	GDSC	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation altering degron motif	0.6471
p.L23P	ACH-000101	Leukemia	CCLE	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation altering degron motif	0.6471
p.L23P	KE-37	haematopoietic and lymphoid tissue	COSMIC	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation altering degron motif	0.6471
p.K19N	ACH-001280	Sarcoma	CCLE	RRKILLLVL	DEG_APCC_DBOX_1	17:25	Mutation altering degron motif	0.5806

Kaplan plot for GAL3ST3 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

GAL3ST3

UniProt ID: Q96A11

Entrez ID: 89792

Protein name: Galactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal3ST3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for GAL3ST3 in