DegronMD - Q96AD5(PNPLA2)

PNPLA2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L481P	DO229013	COCA	ICGC	LLSTPAPE	DEG_SCF_FBW7_2	487:494	Mutation rewiring degron network	0.1667
p.L481P	DO229016	COCA	ICGC	LLSTPAPE	DEG_SCF_FBW7_2	487:494	Mutation rewiring degron network	0.1667
p.L481P	DO229003	COCA	ICGC	LLSTPAPE	DEG_SCF_FBW7_2	487:494	Mutation rewiring degron network	0.1667
p.L481P	DO229005	COCA	ICGC	LLSTPAPE	DEG_SCF_FBW7_2	487:494	Mutation rewiring degron network	0.1667
p.L481P	DO229140	THCA	ICGC	LLSTPAPE	DEG_SCF_FBW7_2	487:494	Mutation rewiring degron network	0.1667
p.L481P	DO229085	THCA	ICGC	LLSTPAPE	DEG_SCF_FBW7_2	487:494	Mutation rewiring degron network	0.1667
p.G483R	SIDM00782	Colorectal Carcinoma	GDSC	LLSTPAPE	DEG_SCF_FBW7_2	487:494	Mutation rewiring degron network	0.2222
p.P477R	SIDM00785	Acute Myeloid Leukemia	GDSC	LLSTPAPE	DEG_SCF_FBW7_2	487:494	Mutation rewiring degron network	0.0556
p.S489I	SIDM01577	Plasma Cell Myeloma	GDSC	LLSTPAPE	DEG_SCF_FBW7_2	487:494	Mutation altering degron motif	0.623
p.H479R	ACH-000990	Endometrial/Uterine Cancer	CCLE	LLSTPAPE	DEG_SCF_FBW7_2	487:494	Mutation rewiring degron network	0.1111
p.E494K	ACH-000990	Endometrial/Uterine Cancer	CCLE	LLSTPAPE	DEG_SCF_FBW7_2	487:494	Mutation altering degron motif	0.7022
p.A492G	ACH-000994	Endometrial/Uterine Cancer	CCLE	LLSTPAPE	DEG_SCF_FBW7_2	487:494	Mutation altering degron motif	0.6429

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*NOTE: the Kaplan plots were collected from OncoLnc