DegronMD - Q96AE4(FUBP1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S99Y	TCGA-13-1497	OV	TCGA	TEEYKVPDGM	DEG_COP1_1	102:111	Mutation blocking phosphorylation signal	0.6944
p.M92I	TCGA-69-7973	LUAD	TCGA	TEEYKVPDGM	DEG_COP1_1	102:111	Mutation rewiring degron network	0.0556
p.M92I	DO23870	LUAD	ICGC	TEEYKVPDGM	DEG_COP1_1	102:111	Mutation rewiring degron network	0.0556
p.P556S	TCGA-FR-A3YN	SKCM	TCGA	APTTT	DEG_SPOP_SBC_1	559:563	Mutation rewiring degron network	0.25
p.P556S	DO38111	SKCM	ICGC	APTTT	DEG_SPOP_SBC_1	559:563	Mutation rewiring degron network	0.25
p.S97R	DO233679	GACA	ICGC	TEEYKVPDGM	DEG_COP1_1	102:111	Mutation rewiring degron network	0.1944
p.S97I	DO233823	GACA	ICGC	TEEYKVPDGM	DEG_COP1_1	102:111	Mutation rewiring degron network	0.1944
p.Q94K	DO228969	LICA	ICGC	TEEYKVPDGM	DEG_COP1_1	102:111	Mutation rewiring degron network	0.1111
p.S120Y	DO31959	OV	ICGC	TEEYKVPDGM	DEG_COP1_1	102:111	Mutation rewiring degron network	0.0833
p.P112L	DO42312	UCEC	ICGC	TEEYKVPDGM	DEG_COP1_1	102:111	Mutation rewiring degron network	0.3056
p.P560S	SIDM00537	Colorectal Carcinoma	GDSC	APTTT	DEG_SPOP_SBC_1	559:563	Mutation altering degron motif	0.5641
p.P560S	ACH-001345	Colon/Colorectal Cancer	CCLE	APTTT	DEG_SPOP_SBC_1	559:563	Mutation altering degron motif	0.5641
p.P560S	GP5d	large intestine	COSMIC	APTTT	DEG_SPOP_SBC_1	559:563	Mutation altering degron motif	0.5641
p.P553S	SIDM00743	Non-Small Cell Lung Carcinoma	GDSC	APTTT	DEG_SPOP_SBC_1	559:563	Mutation rewiring degron network	0.1667
p.P553S	ACH-000448	Lung Cancer	CCLE	APTTT	DEG_SPOP_SBC_1	559:563	Mutation rewiring degron network	0.1667
p.P553S	NCI-H1666	lung	COSMIC	APTTT	DEG_SPOP_SBC_1	559:563	Mutation rewiring degron network	0.1667
p.A557V	SIDM01692	T-Cell Non-Hodgkin's Lymphoma	GDSC	APTTT	DEG_SPOP_SBC_1	559:563	Mutation rewiring degron network	0.2778
p.A557V	ACH-000077	Lymphoma	CCLE	APTTT	DEG_SPOP_SBC_1	559:563	Mutation rewiring degron network	0.2778

Kaplan plot for FUBP1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

FUBP1

UniProt ID: Q96AE4

Entrez ID: 8880

Protein name: Far upstream element-binding protein 1 (FBP) (FUSE-binding protein 1) (DNA helicase V) (hDH V)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for FUBP1 in