DegronMD

Uniprot ID: Q96AE4

Source protein: Far upstream element-binding protein 1

Source gene: FUBP1

Class: DEG_COP1_1

Location: 102:111

E3 ligase: COP1

DEGRON score: 0.6196

ASA_SCORE: 62.24

COIL: 0.3104

CONS_SCORE: 0.3213

DSS_SCORE: 0.4529

HELIX: 0.123

FCONS_SCORE: 0.9354

RIG_SCORE: 0.7754

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S99Y	TCGA-13-1497	OV	TCGA	TEEYKVPDGM	DEG_COP1_1	0.6944
p.M92I	TCGA-69-7973	LUAD	TCGA	TEEYKVPDGM	DEG_COP1_1	0.0556
p.M92I	DO23870	LUAD	ICGC	TEEYKVPDGM	DEG_COP1_1	0.0556
p.S97R	DO233679	GACA	ICGC	TEEYKVPDGM	DEG_COP1_1	0.1944
p.S97I	DO233823	GACA	ICGC	TEEYKVPDGM	DEG_COP1_1	0.1944
p.Q94K	DO228969	LICA	ICGC	TEEYKVPDGM	DEG_COP1_1	0.1111
p.S120Y	DO31959	OV	ICGC	TEEYKVPDGM	DEG_COP1_1	0.0833
p.P112L	DO42312	UCEC	ICGC	TEEYKVPDGM	DEG_COP1_1	0.3056

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96AE4	Far upstream element-binding protein 1	DEG_COP1_1	102:111	TEEYKVPDGM	COP1	0.6196	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons