DegronMD - Q96CT7(CCDC124)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E101A	TCGA-AX-A1C4	UCEC	TCGA	VATSS	DEG_SPOP_SBC_1	89:93	Mutation rewiring degron network	0.1111
p.E101A	DO42480	UCEC	ICGC	VATSS	DEG_SPOP_SBC_1	89:93	Mutation rewiring degron network	0.1111
p.R97W	TCGA-AX-A2HD	UCEC	TCGA	VATSS	DEG_SPOP_SBC_1	89:93	Mutation rewiring degron network	0.2222
p.R97W	DO42608	UCEC	ICGC	VATSS	DEG_SPOP_SBC_1	89:93	Mutation rewiring degron network	0.2222
p.R97W	ACH-000974	Endometrial/Uterine Cancer	CCLE	VATSS	DEG_SPOP_SBC_1	89:93	Mutation rewiring degron network	0.2222
p.R97W	ACH-002026	Endometrial/Uterine Cancer	CCLE	VATSS	DEG_SPOP_SBC_1	89:93	Mutation rewiring degron network	0.2222
p.T91M	TCGA-L5-A4OH	ESCA	TCGA	VATSS	DEG_SPOP_SBC_1	89:93	Mutation altering degron motif	0.7423
p.R88L	DO228985	LICA	ICGC	VATSS	DEG_SPOP_SBC_1	89:93	Mutation rewiring degron network	0.3056
p.D102N	DO222904	MELA	ICGC	VATSS	DEG_SPOP_SBC_1	89:93	Mutation rewiring degron network	0.0833
p.V95A	DO228138	PBCA	ICGC	VATSS	DEG_SPOP_SBC_1	89:93	Mutation rewiring degron network	0.2778
p.A86V	DO232761	PBCA	ICGC	VATSS	DEG_SPOP_SBC_1	89:93	Mutation rewiring degron network	0.25
p.D102V	ACH-000844	Lung Cancer	CCLE	VATSS	DEG_SPOP_SBC_1	89:93	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons