DegronMD - Q96CX2(KCTD12)

KCTD12

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R184H	TCGA-K4-A5RJ	BLCA	TCGA	PLLTPSQS	DEG_SCF_FBW7_1	193:200	Mutation rewiring degron network	0.0833
p.R184H	DO49784	BLCA	ICGC	PLLTPSQS	DEG_SCF_FBW7_1	193:200	Mutation rewiring degron network	0.0833
p.D202E	DO229046	LICA	ICGC	PLLTPSQS	DEG_SCF_FBW7_1	193:200	Mutation rewiring degron network	0.2778
p.P193R	DO229135	LMS	ICGC	PLLTPSQS	DEG_SCF_FBW7_1	193:200	Mutation altering degron motif	0.7512
p.A191V	DO229224	THCA	ICGC	PLLTPSQS	DEG_SCF_FBW7_1	193:200	Mutation rewiring degron network	0.2778
p.R206L	DO229248	THCA	ICGC	PLLTPSQS	DEG_SCF_FBW7_1	193:200	Mutation rewiring degron network	0.1667
p.T196A	DO229250	THCA	ICGC	PLLTPSQS	DEG_SCF_FBW7_1	193:200	Mutation altering degron motif	0.825
p.S204N	DO230449	UTCA	ICGC	PLLTPSQS	DEG_SCF_FBW7_1	193:200	Mutation blocking phosphorylation signal	0.6667

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*NOTE: the Kaplan plots were collected from OncoLnc