DegronMD - Q96D05(FAM241B)

GO - Biological processes (BP): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T21A	SIDM00661	B-Cell Non-Hodgkin's Lymphoma	GDSC	VRTTT	DEG_SPOP_SBC_1	18:22	Mutation altering degron motif	0.7139
p.T21A	SIDM00667	Other Sarcomas	GDSC	VRTTT	DEG_SPOP_SBC_1	18:22	Mutation altering degron motif	0.7139
p.D15N	SIDM00319	Melanoma	GDSC	VRTTT	DEG_SPOP_SBC_1	18:22	Mutation rewiring degron network	0.25
p.D15N	VMRC-MELG	skin	COSMIC	VRTTT	DEG_SPOP_SBC_1	18:22	Mutation rewiring degron network	0.25
p.R31G	SIDM00481	Ovarian Carcinoma	GDSC	VRTTT	DEG_SPOP_SBC_1	18:22	Mutation rewiring degron network	0.0833
p.R31G	OAW-28	ovary	COSMIC	VRTTT	DEG_SPOP_SBC_1	18:22	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons