DegronMD - Q96DU7(ITPKC)

ITPKC

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E335K	TCGA-13-1496	OV	TCGA	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation altering degron motif	0.591
p.E335K	DO31899	OV	ICGC	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation altering degron motif	0.591
p.I331N	TCGA-D3-A2JH	SKCM	TCGA	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation rewiring degron network	0.25
p.I331N	DO47263	SKCM	ICGC	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation rewiring degron network	0.25
p.A341V	TCGA-VQ-A922	STAD	TCGA	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation rewiring degron network	0.3056
p.A341V	DO51794	STAD	ICGC	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation rewiring degron network	0.3056
p.E335D	TCGA-VS-A953	CESC	TCGA	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation altering degron motif	0.5647
p.E335D	DO219727	CESC	ICGC	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation altering degron motif	0.5647
p.A341S	DO229037	LICA	ICGC	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation rewiring degron network	0.3056
p.P337S	DO232761	PBCA	ICGC	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation altering degron motif	0.6752
p.P334L	SIDM00121	T-Lymphoblastic Leukemia	GDSC	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation altering degron motif	0.6471
p.P334L	ACH-001738	Leukemia	CCLE	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation altering degron motif	0.6471
p.P334L	CCRF-CEM	haematopoietic and lymphoid tissue	COSMIC	PETPEPE	DEG_SCF_FBW7_2	334:340	Mutation altering degron motif	0.6471

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*NOTE: the Kaplan plots were collected from OncoLnc