DegronMD - Q96FA7(ZBED10P)

ZBED10P

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P231L	TCGA-W3-AA1V	SKCM	TCGA	ICLTPHRS	DEG_SCF_FBW7_1	227:234	Mutation altering degron motif	0.7582
p.P231L	DO51276	SKCM	ICGC	ICLTPHRS	DEG_SCF_FBW7_1	227:234	Mutation altering degron motif	0.7582
p.L235V	DO50406	ESAD	ICGC	ICLTPHRS	DEG_SCF_FBW7_1	227:234	Mutation rewiring degron network	0.3056
p.P231R	DO232555	PBCA	ICGC	ICLTPHRS	DEG_SCF_FBW7_1	227:234	Mutation altering degron motif	0.7512
p.E221Q	DO229475	SKCA	ICGC	ICLTPHRS	DEG_SCF_FBW7_1	227:234	Mutation rewiring degron network	0.1667
p.A222G	DO229184	THCA	ICGC	ICLTPHRS	DEG_SCF_FBW7_1	227:234	Mutation rewiring degron network	0.1944
p.P224T	SIDM00837	Colorectal Carcinoma	GDSC	ICLTPHRS	DEG_SCF_FBW7_1	227:234	Mutation rewiring degron network	0.25
p.P224T	ACH-000958	Colon/Colorectal Cancer	CCLE	ICLTPHRS	DEG_SCF_FBW7_1	227:234	Mutation rewiring degron network	0.25
p.P224T	SW48	large intestine	COSMIC	ICLTPHRS	DEG_SCF_FBW7_1	227:234	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc