DegronMD - Q96FE7(PIK3IP1)

PIK3IP1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q107H	TCGA-A5-A0G1	UCEC	TCGA	PETTS	DEG_SPOP_SBC_1	102:106	Mutation rewiring degron network	0.3056
p.A111T	TCGA-BS-A0UV	UCEC	TCGA	PETTS	DEG_SPOP_SBC_1	102:106	Mutation rewiring degron network	0.1944
p.E115K	TCGA-VS-A9UA	CESC	TCGA	PETTS	DEG_SPOP_SBC_1	102:106	Mutation rewiring degron network	0.0833
p.G106A	DO219052	BLCA	ICGC	PETTS	DEG_SPOP_SBC_1	102:106	Mutation altering degron motif	0.754
p.G106E	DO2281	BRCA	ICGC	PETTS	DEG_SPOP_SBC_1	102:106	Mutation altering degron motif	0.7199
p.A104V	DO8151	COAD	ICGC	PETTS	DEG_SPOP_SBC_1	102:106	Mutation altering degron motif	0.6936
p.I105M	DO233189	GACA	ICGC	PETTS	DEG_SPOP_SBC_1	102:106	Mutation altering degron motif	0.7618
p.S114Y	DO37831	SKCM	ICGC	PETTS	DEG_SPOP_SBC_1	102:106	Mutation rewiring degron network	0.1111
p.G95C	DO37421	SKCM	ICGC	PETTS	DEG_SPOP_SBC_1	102:106	Mutation rewiring degron network	0.1389
p.G108D	DO41752	UCEC	ICGC	PETTS	DEG_SPOP_SBC_1	102:106	Mutation rewiring degron network	0.2778
p.R94P	SIDM00881	Breast Carcinoma	GDSC	PETTS	DEG_SPOP_SBC_1	102:106	Mutation rewiring degron network	0.1111
p.R94P	ACH-000352	Breast Cancer	CCLE	PETTS	DEG_SPOP_SBC_1	102:106	Mutation rewiring degron network	0.1111
p.R94P	HCC1428	breast	COSMIC	PETTS	DEG_SPOP_SBC_1	102:106	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc