DegronMD - Q96FL9(GALNT14)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V33L	TCGA-05-4420	LUAD	TCGA	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1667
p.V33L	DO24675	LUAD	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1667
p.R29S	TCGA-28-5211	GBM	TCGA	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.0556
p.R29S	DO11016	GBM	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.0556
p.R47Q	DO8063	COAD	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.2778
p.A47T	DO8192	COAD	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.2778
p.D46N	DO8400	COAD	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.3056
p.G53A	DO227987	COCA	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1111
p.S46P	DO50337	ESAD	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.3056
p.W49R	DO234333	ESAD	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.2222
p.S54R	DO233618	GACA	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.0833
p.P37T	DO229027	LICA	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.2778
p.P34T	DO229036	LICA	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1944
p.V33M	DO229177	LMS	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1667
p.S49R	DO25927	LUAD	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.2222
p.S53F	DO220878	MELA	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1111
p.S45L	DO220897	MELA	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation altering degron motif	0.7667
p.S45L	DO223907	SKCM	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation altering degron motif	0.7667
p.S45L	DO38201	STAD	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation altering degron motif	0.7667
p.S45L	DO41542	UCEC	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation altering degron motif	0.7667
p.D51N	DO218848	SKCA	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1667
p.D51N	DO38123	SKCM	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1667
p.Q46P	DO48770	SKCM	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.3056
p.P44S	DO229259	THCA	ICGC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation altering degron motif	0.5641
p.A52S	SIDM00555	Glioblastoma	GDSC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1389
p.A52S	KS-1	central nervous system	COSMIC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1389
p.L52P	SIDM01588	Endometrial Carcinoma	GDSC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1389
p.L52P	ACH-000993	Endometrial/Uterine Cancer	CCLE	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1389
p.K46N	639-V	urinary tract	COSMIC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.3056
p.R39W	SNU-1040	large intestine	COSMIC	VQTPKPS	DEG_SCF_FBW7_1	39:45	Mutation altering degron motif	0.8634

Kaplan plot for GALNT14 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

GALNT14

UniProt ID: Q96FL9

Entrez ID: 79623

Protein name: Polypeptide N-acetylgalactosaminyltransferase 14 (EC 2.4.1.41) (Polypeptide GalNAc transferase 14) (GalNAc-T14) (pp-GaNTase 14) (Protein-UDP acetylgalactosaminyltransferase 14) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for GALNT14 in