DegronMD - Q96HH9(GRAMD2B)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K54N	SIDM00327	Hodgkin's Lymphoma	GDSC	PTPSVE	DEG_SCF_FBW7_2	50:55	Mutation altering degron motif	0.6918
p.K54N	L-428	haematopoietic and lymphoid tissue	COSMIC	PTPSVE	DEG_SCF_FBW7_2	50:55	Mutation altering degron motif	0.6918
p.A56V	KCL-22	haematopoietic and lymphoid tissue	COSMIC	PTPSVE	DEG_SCF_FBW7_2	50:55	Mutation rewiring degron network	0.3056
p.R50W	KCL-22	haematopoietic and lymphoid tissue	COSMIC	PTPSVE	DEG_SCF_FBW7_2	50:55	Mutation altering degron motif	0.8634
p.A40V	KCL-22	haematopoietic and lymphoid tissue	COSMIC	PTPSVE	DEG_SCF_FBW7_2	50:55	Mutation substituting flanking lysine	0.1667
p.R50Q	Mewo	skin	COSMIC	PTPSVE	DEG_SCF_FBW7_2	50:55	Mutation altering degron motif	0.7329

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons