DegronMD - Q96IZ5(RBM41)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G228R	TCGA-64-1679	LUAD	TCGA	DSGTAES	DEG_SCF_TRCP1_1	226:232	Mutation altering degron motif	0.7568
p.G228R	DO26200	LUAD	ICGC	DSGTAES	DEG_SCF_TRCP1_1	226:232	Mutation altering degron motif	0.7568
p.G228D	TCGA-B5-A3FA	UCEC	TCGA	DSGTAES	DEG_SCF_TRCP1_1	226:232	Mutation altering degron motif	0.7198
p.G228D	DO52402	UCEC	ICGC	DSGTAES	DEG_SCF_TRCP1_1	226:232	Mutation altering degron motif	0.7198
p.Q230K	DO48423	BLCA	ICGC	DSGTAES	DEG_SCF_TRCP1_1	226:232	Mutation altering degron motif	0.6944
p.L231I	DO229015	LICA	ICGC	DSGTAES	DEG_SCF_TRCP1_1	226:232	Mutation altering degron motif	0.7174
p.A221D	DO229037	LICA	ICGC	DSGTAES	DEG_SCF_TRCP1_1	226:232	Mutation rewiring degron network	0.1944
p.L231R	DO230937	LUSC	ICGC	DSGTAES	DEG_SCF_TRCP1_1	226:232	Mutation altering degron motif	0.8428
p.F216C	DO40884	UCEC	ICGC	DSGTAES	DEG_SCF_TRCP1_1	226:232	Mutation rewiring degron network	0.0556
p.I221T	DO49073	UCEC	ICGC	DSGTAES	DEG_SCF_TRCP1_1	226:232	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons