DegronMD - Q96J87(CELF6)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A37T	TCGA-VQ-A8PT	STAD	TCGA	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.1389
p.A37T	DO51776	STAD	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.1389
p.M29I	DO224768	BRCA	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation altering degron motif	0.6507
p.F39L	DO224855	BRCA	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.0833
p.R37H	DO222574	BTCA	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.1389
p.R19Q	DO49887	CESC	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.1944
p.R19Q	DO229030	LICA	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.1944
p.A37V	DO233034	GACA	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.1389
p.G31R	DO233693	GACA	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.3056
p.D34N	DO11854	GBM	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.2222
p.M25I	DO228225	LICA	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation altering degron motif	0.7618
p.G28R	DO228359	LICA	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation altering degron motif	0.6457
p.L15I	DO228948	LICA	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.0833
p.Q30K	DO229015	LICA	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation altering degron motif	0.6944
p.L17I	DO229045	LICA	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.1389
p.R15Q	DO23244	LINC	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.0833
p.E33K	DO229130	NKTL	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.25
p.P14T	DO229248	THCA	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.0556
p.V35I	DO41638	UCEC	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.1944
p.G31C	DO41584	UCEC	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.3056
p.G14D	DO41235	UCEC	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.0556
p.V14F	DO41271	UCEC	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.0556
p.L26M	DO42472	UCEC	ICGC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation altering degron motif	0.711
p.M40T	SIDM00926	Non-Small Cell Lung Carcinoma	GDSC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.0556
p.M40T	SIDM00672	Hepatocellular Carcinoma	GDSC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.0556
p.M40T	SIDM01090	Colorectal Carcinoma	GDSC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.0556
p.M40T	SIDM00210	Ovarian Carcinoma	GDSC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.0556
p.M40T	SIDM00309	Mesothelioma	GDSC	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.0556
p.N33T	ACH-000361	Liver Cancer	CCLE	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.25
p.P36L	ACH-000568	Breast Cancer	CCLE	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.1667
p.P36S	ACH-000568	Breast Cancer	CCLE	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.1667
p.R17L	ACH-001767	Non-Cancerous	CCLE	DSGVGMS	DEG_SCF_TRCP1_1	24:30	Mutation rewiring degron network	0.1389

Kaplan plot for CELF6 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CELF6

UniProt ID: Q96J87

Entrez ID: 60677

Protein name: CUGBP Elav-like family member 6 (CELF-6) (Bruno-like protein 6) (CUG-BP- and ETR-3-like factor 6) (RNA-binding protein BRUNOL-6)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CELF6 in