DegronMD - Q96K17(BTF3L4)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L145I	TCGA-24-1846	OV	TCGA	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation altering degron motif	0.6063
p.N148K	TCGA-EO-A22U	UCEC	TCGA	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation rewiring degron network	0.25
p.N148K	DO43755	UCEC	ICGC	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation rewiring degron network	0.25
p.V146G	TCGA-PK-A5HB	ACC	TCGA	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation rewiring degron network	0.3056
p.D141G	TCGA-XF-AAMJ	BLCA	TCGA	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation altering degron motif	0.6087
p.D141G	DO51932	BLCA	ICGC	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation altering degron motif	0.6087
p.A152V	DO222427	BTCA	ICGC	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation rewiring degron network	0.1389
p.D150Y	DO228952	LICA	ICGC	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation rewiring degron network	0.1944
p.D139Y	SIDM00789	Colorectal Carcinoma	GDSC	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation altering degron motif	0.6214
p.D139Y	ACH-000997	Colon/Colorectal Cancer	CCLE	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation altering degron motif	0.6214
p.D139Y	ACH-001061	Colon/Colorectal Cancer	CCLE	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation altering degron motif	0.6214
p.D139Y	HCT-15	large intestine	COSMIC	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation altering degron motif	0.6214
p.D134Y	SIDM00534	Colorectal Carcinoma	GDSC	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation rewiring degron network	0.2778
p.D134Y	ACH-000986	Colon/Colorectal Cancer	CCLE	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation rewiring degron network	0.2778
p.D134Y	HT-115	large intestine	COSMIC	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation rewiring degron network	0.2778
p.D134H	ACH-000029	Lung Cancer	CCLE	DEEDDDVPDL	DEG_COP1_1	136:145	Mutation rewiring degron network	0.2778

Kaplan plot for BTF3L4 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

BTF3L4

UniProt ID: Q96K17

Entrez ID: 91408

Protein name: Transcription factor BTF3 homolog 4 (Basic transcription factor 3-like 4)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for BTF3L4 in