DegronMD - Q96K30(RITA1)

RITA1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R155C	TCGA-CD-8536	STAD	TCGA	LLWTPPPT	DEG_SCF_FBW7_1	140:147	Mutation rewiring degron network	0.1111
p.G150V	TCGA-LG-A6GG	LIHC	TCGA	LLWTPPPT	DEG_SCF_FBW7_1	140:147	Mutation rewiring degron network	0.25
p.A146T	SIDM00216	Colorectal Carcinoma	GDSC	LLWTPPPT	DEG_SCF_FBW7_1	140:147	Mutation altering degron motif	0.7139
p.A146T	SNU-175	large intestine	COSMIC	LLWTPPPT	DEG_SCF_FBW7_1	140:147	Mutation altering degron motif	0.7139
p.R152W	SIDM01016	T-Lymphoblastic Leukemia	GDSC	LLWTPPPT	DEG_SCF_FBW7_1	140:147	Mutation rewiring degron network	0.1944
p.R152W	Jurkat	haematopoietic and lymphoid tissue	COSMIC	LLWTPPPT	DEG_SCF_FBW7_1	140:147	Mutation rewiring degron network	0.1944
p.R152Q	SIDM00217	Colorectal Carcinoma	GDSC	LLWTPPPT	DEG_SCF_FBW7_1	140:147	Mutation rewiring degron network	0.1944
p.R152Q	SNU-1040	large intestine	COSMIC	LLWTPPPT	DEG_SCF_FBW7_1	140:147	Mutation rewiring degron network	0.1944
p.P131L	SIDM01615	Non-Small Cell Lung Carcinoma	GDSC	LLWTPPPT	DEG_SCF_FBW7_1	140:147	Mutation substituting flanking lysine	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc