DegronMD - Q96KG7(MEGF10)

MEGF10

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S1128T	TCGA-13-1403	OV	TCGA	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation altering degron motif	0.8227
p.S1128T	DO28038	OV	ICGC	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation altering degron motif	0.8227
p.D1127Y	TCGA-97-7546	LUAD	TCGA	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation altering degron motif	0.7325
p.D1127Y	DO23762	LUAD	ICGC	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation altering degron motif	0.7325
p.S1120L	TCGA-EE-A182	SKCM	TCGA	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation rewiring degron network	0.1389
p.S1120L	DO37814	SKCM	ICGC	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation rewiring degron network	0.1389
p.S1121F	TCGA-WE-A8JZ	SKCM	TCGA	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation rewiring degron network	0.1667
p.S1121F	DO51279	SKCM	ICGC	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation rewiring degron network	0.1667
p.S1131G	SIDM00216	Colorectal Carcinoma	GDSC	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation altering degron motif	0.5882
p.S1131G	ACH-000989	Colon/Colorectal Cancer	CCLE	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation altering degron motif	0.5882
p.S1133T	SIDM00084	Glioblastoma	GDSC	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation altering degron motif	0.7116
p.S1128I	SIDM00339	Non-Small Cell Lung Carcinoma	GDSC	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation altering degron motif	0.8453
p.S1128I	ACH-000787	Lung Cancer	CCLE	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation altering degron motif	0.8453
p.S1128I	LXF-289	lung	COSMIC	DSGGSSS	DEG_SCF_TRCP1_1	1127:1133	Mutation altering degron motif	0.8453

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*NOTE: the Kaplan plots were collected from OncoLnc