DegronMD - Q96KN7(RPGRIP1)

RPGRIP1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A181V	TCGA-AA-3984	COAD	TCGA	DRLSYTAPP	CBL_PTK	167:175	Mutation rewiring degron network	0.1667
p.A181V	DO9002	COAD	ICGC	DRLSYTAPP	CBL_PTK	167:175	Mutation rewiring degron network	0.1667
p.A181V	SIDM01026	Esophageal Squamous Cell Carcinoma	GDSC	DRLSYTAPP	CBL_PTK	167:175	Mutation rewiring degron network	0.1667
p.A181V	ACH-000824	Esophageal Cancer	CCLE	DRLSYTAPP	CBL_PTK	167:175	Mutation rewiring degron network	0.1667
p.A181V	KYSE-510	oesophagus	COSMIC	DRLSYTAPP	CBL_PTK	167:175	Mutation rewiring degron network	0.1667
p.P174A	TCGA-DU-8166	LGG	TCGA	DRLSYTAPP	CBL_PTK	167:175	Mutation altering degron motif	0.6392
p.P174A	DO22215	LGG	ICGC	DRLSYTAPP	CBL_PTK	167:175	Mutation altering degron motif	0.6392
p.R168K	TCGA-MI-A75G	LIHC	TCGA	DRLSYTAPP	CBL_PTK	167:175	Mutation altering degron motif	0.6126
p.R168K	DO49709	LIHC	ICGC	DRLSYTAPP	CBL_PTK	167:175	Mutation altering degron motif	0.6126
p.S176L	DO228998	LICA	ICGC	DRLSYTAPP	CBL_PTK	167:175	Mutation rewiring degron network	0.3056
p.D167Y	DO229029	LICA	ICGC	DRLSYTAPP	CBL_PTK	167:175	Mutation altering degron motif	0.7325
p.A181G	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	DRLSYTAPP	CBL_PTK	167:175	Mutation rewiring degron network	0.1667
p.D167G	ACH-000982	Colon/Colorectal Cancer	CCLE	DRLSYTAPP	CBL_PTK	167:175	Mutation altering degron motif	0.7198

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*NOTE: the Kaplan plots were collected from OncoLnc