DegronMD - Q96L12(CALR3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.F27C	TCGA-EO-A3AV	UCEC	TCGA	LRVALATVY	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.1944
p.F27C	DO52412	UCEC	ICGC	LRVALATVY	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.1944
p.E25Q	TCGA-Q9-A6FW	ESCA	TCGA	LRVALATVY	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.25
p.G30R	DO233233	GACA	ICGC	LRVALATVY	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.1111
p.V6G	DO233764	GACA	ICGC	LRVALATVY	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.1111
p.C12R	DO227933	PBCA	ICGC	LRVALATVY	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.2778
p.M13V	SIDM01246	Ewing's Sarcoma	GDSC	LRVALATVY	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.3056
p.M13V	SIDM00634	Ewing's Sarcoma	GDSC	LRVALATVY	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.3056
p.M13V	ACH-002160	Bone Cancer	CCLE	LRVALATVY	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.3056
p.M13V	MC-IXC	autonomic ganglia	COSMIC	LRVALATVY	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.3056
p.A10T	SIDM01559	Melanoma	GDSC	LRVALATVY	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.2222
p.A10T	ACH-000296	Colon/Colorectal Cancer	CCLE	LRVALATVY	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons