DegronMD - Q96LL4(C8orf48)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N27T	TCGA-D1-A17Q	UCEC	TCGA	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.1944
p.N27T	DO41903	UCEC	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.1944
p.S41Y	TCGA-G4-6628	COAD	TCGA	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.1944
p.S41Y	DO10132	COAD	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.1944
p.N27K	TCGA-KN-8428	KICH	TCGA	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.1944
p.N27K	DO220484	KICH	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.1944
p.R44W	DO1138	BRCA	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.1111
p.R44W	DO222706	COCA	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.1111
p.R44Q	DO2647	BRCA	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.1111
p.S39G	DO227646	COCA	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.25
p.S28F	DO229010	COCA	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.2222
p.S28F	DO229013	COCA	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.2222
p.S28F	DO229016	COCA	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.2222
p.S28F	DO229003	COCA	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.2222
p.S28F	DO229005	COCA	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.2222
p.S28F	DO234285	ESAD	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.2222
p.G43A	DO233865	GACA	ICGC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.1389
p.T29A	SIDM02069	Colorectal Carcinoma	GDSC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.25
p.E23G	SIDM00282	Colorectal Carcinoma	GDSC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.0833
p.E23G	ACH-000998	Colon/Colorectal Cancer	CCLE	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.0833
p.T29S	SIDM00382	Glioblastoma	GDSC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.25
p.T29S	ACH-000609	Brain Cancer	CCLE	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.25
p.E31K	SIDM00870	Breast Carcinoma	GDSC	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.3056
p.E31K	ACH-000725	Breast Cancer	CCLE	VQTSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.3056

DegronMD: protein-targeted degradation, mutation and drug response to degrons

C8orf48

UniProt ID: Q96LL4

Entrez ID: 157773

Protein name: Uncharacterized protein C8orf48

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for C8orf48 in