DegronMD - Q96LL9(DNAJC30)

DNAJC30

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D149N	DO223004	ESCA	ICGC	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation rewiring degron network	0.1944
p.S145Y	DO36556	READ	ICGC	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation rewiring degron network	0.3056
p.G150A	SIDM00625	Other Sarcomas	GDSC	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation rewiring degron network	0.1667
p.G150A	ACH-000449	Sarcoma	CCLE	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation rewiring degron network	0.1667
p.G150A	MES-SA	soft tissue	COSMIC	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation rewiring degron network	0.1667
p.P133L	SIDM00345	Non-Small Cell Lung Carcinoma	GDSC	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation rewiring degron network	0.1944
p.S154F	SIDM01190	Bladder Carcinoma	GDSC	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation rewiring degron network	0.0556
p.S154F	ACH-000720	Bladder Cancer	CCLE	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation rewiring degron network	0.0556
p.S154F	TCCSUP	urinary tract	COSMIC	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation rewiring degron network	0.0556
p.R152G	SIDM00150	Colorectal Carcinoma	GDSC	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation rewiring degron network	0.1111
p.R152G	ACH-000969	Colon/Colorectal Cancer	CCLE	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation rewiring degron network	0.1111
p.R152G	KM12	large intestine	COSMIC	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation rewiring degron network	0.1111
p.R139P	SIDM01582	Gastric Carcinoma	GDSC	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation altering degron motif	0.6401
p.R139P	ACH-000507	Gastric Cancer	CCLE	PRTPPPT	DEG_SCF_FBW7_1	138:144	Mutation altering degron motif	0.6401

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*NOTE: the Kaplan plots were collected from OncoLnc