DegronMD - Q96LR2(LURAP1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G125C	TCGA-17-Z045	LUAD	TCGA	PDTST	DEG_SPOP_SBC_1	131:135	Mutation rewiring degron network	0.1667
p.P131T	TCGA-28-1757	GBM	TCGA	PDTST	DEG_SPOP_SBC_1	131:135	Mutation altering degron motif	0.7031
p.P131T	DO12166	GBM	ICGC	PDTST	DEG_SPOP_SBC_1	131:135	Mutation altering degron motif	0.7031
p.D137N	TCGA-2W-A8YY	CESC	TCGA	PDTST	DEG_SPOP_SBC_1	131:135	Mutation rewiring degron network	0.2778
p.D137N	DO223732	CESC	ICGC	PDTST	DEG_SPOP_SBC_1	131:135	Mutation rewiring degron network	0.2778
p.R121C	TCGA-AZ-6601	COAD	TCGA	PDTST	DEG_SPOP_SBC_1	131:135	Mutation rewiring degron network	0.0556
p.R121C	DO8119	COAD	ICGC	PDTST	DEG_SPOP_SBC_1	131:135	Mutation rewiring degron network	0.0556
p.R121S	TCGA-BF-A1PZ	SKCM	TCGA	PDTST	DEG_SPOP_SBC_1	131:135	Mutation rewiring degron network	0.0556
p.R121S	DO50279	SKCM	ICGC	PDTST	DEG_SPOP_SBC_1	131:135	Mutation rewiring degron network	0.0556
p.R124L	DO228976	LICA	ICGC	PDTST	DEG_SPOP_SBC_1	131:135	Mutation rewiring degron network	0.1389
p.R124Q	ACH-001548	Neuroblastoma	CCLE	PDTST	DEG_SPOP_SBC_1	131:135	Mutation rewiring degron network	0.1389
p.S143F	ACH-002045	Head and Neck Cancer	CCLE	PDTST	DEG_SPOP_SBC_1	131:135	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons