DegronMD - Q96LZ2(MAGEB10)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H79N	TCGA-49-AAR9	LUAD	TCGA	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.1111
p.H79N	DO218921	LUAD	ICGC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.1111
p.N59T	TCGA-AP-A1DV	UCEC	TCGA	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.1111
p.N59T	DO43186	UCEC	ICGC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.1111
p.N59T	ACH-001991	Primary	CCLE	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.1111
p.A74V	TCGA-AX-A2HD	UCEC	TCGA	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.25
p.A74V	DO42608	UCEC	ICGC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.25
p.P61L	TCGA-B5-A3FC	UCEC	TCGA	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.1667
p.P61L	DO41871	UCEC	ICGC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.1667
p.G63E	TCGA-FW-A3R5	SKCM	TCGA	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.2222
p.G63E	DO37406	SKCM	ICGC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.2222
p.Q68K	TCGA-NJ-A4YQ	LUAD	TCGA	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation altering degron motif	0.5833
p.Q68K	DO218944	LUAD	ICGC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation altering degron motif	0.5833
p.E66K	TCGA-ZF-AA4V	BLCA	TCGA	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.3056
p.E66K	DO219087	BLCA	ICGC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.3056
p.A57E	DO227977	COCA	ICGC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.0556
p.A77S	DO229019	LICA	ICGC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.1667
p.H62L	DO229177	LMS	ICGC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.1944
p.R65Q	DO230529	LUSC	ICGC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.2778
p.G63R	SIDM00850	Gastric Carcinoma	GDSC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.2222
p.G63R	ACH-000880	Gastric Cancer	CCLE	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.2222
p.G63R	AGS	stomach	COSMIC	AQSTS	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.2222

Kaplan plot for MAGEB10 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MAGEB10

UniProt ID: Q96LZ2

Entrez ID: 139422

Protein name: Melanoma-associated antigen B10 (MAGE-B10 antigen)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MAGEB10 in